The highly-studied, human p53 gene is known to play a key role in cellular stress response mechanisms by converting a variety of different stimuli into cell growth arrest or apoptosis (cell death). Such stimuli may include DNA damaging conditions, like gamma-irradiation, deregulation of transcription or replication, and oncogene transformation.
Most anti-cancer therapies meant to target cancerous cells also damage or kill normal cells containing native p53, causing severe side...
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